GCMS-TQ8040 NX

Газовые хроматомасс-спектрометры Масс-спектрометрия Сверхбыстрая масс-спектрометрия

Трехквадрупольный газовый хроматомасс-спектрометр GCMS-TQ8040 NX

Описание
Performance
Operation
Productivity
Optional Units
Videos

Описание

Квадрупольные газовые хроматомасс-спектрометры серии NX созданы на базе газового хроматографа Nexis GC-2030 и квадрупольных масс-селективных детекторов, которые используются в моделях GCMS-QP2020, GCMS-TQ8040 и GCMS-TQ8050. Как и все последние модели, серия NX относится к серии сверхбыстрых масс-спектрометров (UFMS).
Сочетание новейшего газового хроматографа Nexis GC-2030 и апробированной модели масс-детектора даёт производительную и удобную в эксплуатации ГХМС систему — трехквадрупольный газовый хроматомасс-спектрометр GCMS-TQ8040 NX.

Smart Performance
Equipped with an ion source that features high sensitivity and long-term stability, and a high-efficiency collision cell, the system can provide sensitive, stable analyses over a long period of time. Also, since it incorporates the Nexis™ GC-2030, high-precision control over flowrate and temperature is assured, enabling the acquisition of highly reliable data.

Smart Productivity
The GC/MS is now a standard system for analysts, and a system can be used for a wide variety of applications. The active time management feature appropriately manages times when the system requires maintenance, or when system changes are being made, or the waiting time for a user when multiple users are waiting to use the system. This ensures more efficient use of the system and greater uptime.

Smart Operation
Creating an MRM analysis method requires determining the optimum transitions, collision energies, and other complicated parameters. In GCMSsolution™ software, Smart MRM, the method creation function, creates optimized analytical methods by using the transitions data in the «Smart Database» file. When you want to perform MRM measurements of components not contained in the database, the optimal transitions can be automatically searched for using the MRM Optimization Tool.

► Газовые хроматомасс-спектрометры серии NX, листовка

Performance

Smart Performance

Equipped with an ion source that features high sensitivity and long-term stability, and a high-efficiency collision cell, the system can provide sensitive, stable analyses over a long period of time. Also, since it incorporates the Nexis™ GC-2030, high-precision control over flowrate and temperature is assured, enabling the acquisition of highly reliable data.

Highly Sensitive and Stable Ion Source
The effect of the filament’s electric potential on the ion source is reduced by placing more distance between the filament and ion source box. In addition, a shield blocks out radiant heat generated from the filament to ensure the ion source box temperature remains uniform. Since this prevents any active spots within the ion source, it provides higher sensitivity for analysis.
(Patent: US7939810)

New Flow Controller Achieves Exceptional Reproducibility
A new flow controller (AFC) with a CPU uses various control methods to control carrier gas flow to a constant flow speed, flowrate, or pressure. It can also accurately trace the analytical conditions already being used. The split line filter can be replaced without any tools. Internal contamination can be confirmed visually, ensuring filters are replaced at the proper time.

One Touch Inlet Maintenance
The injection port can be opened or closed without tools by simply sliding the ClickTek™ lever. Replace the insert, slide the lever and feel the click for a leak-free install every time.

High-Performance Quadrupole Mass Filter
The high-accuracy mass filter with pre-rods and patented electric field control technology achieves high-accuracy mass separation performance. Also, the pre-rods minimize quadrupole contamination and eliminate the need for quadrupole maintenance.

Advanced GC Oven
The improved temperature control function enables more precise temperature control of the GC oven, which improves the precision of retention time reproducibility. In addition, three oven cooling rate levels can be specified to minimize damage to column liquid phases and maximize the service life.

Technology That Makes Possible the Simultaneous Analysis of Several Hundred Components
OFF-AXIS Ion Optics
Lower detection limits are achieved by collision cell and OFF-AXIS Ion Optics, a patent technology, which is capable of bending the axis of Q3 pre-rod. Meta-stable and neutral ions are removed without sacrificing sensitivity.

High-Efficiency Collision Cell UFsweeper™
Shimadzu’s proprietary UFsweeper technology achieves high-speed MRM analysis at speeds up to 800 transitions per second. It sweeps residual ions from the collision cell to provide high-efficiency CID and fast ion transport. Rapid ion removal minimizes cross-talk and enables trace analysis.

Automatic Method Creation
Smart MRM™ is a function that sets the optimal measurement time for each component, and automatically creates a method. Since only the data during the elution times of the targeted components is acquired, even when simultaneously analyzing several hundred components, detection occurs without any loss in sensitivity, even with trace concentrations.

High-Sensitivity Analysis by Single GC-MS Mode
Due to a highly sensitive ion source and highly sensitive detector with overdrive lenses, the GCMS-TQ8040 NX is able to select and detect generated ions efficiently. That achieves high sensitivity not only for MRM measurements in the GC-MS/MS mode, but also for scan and SIM measurements in the GC/MS mode. In addition, pre-rods help prevent quadrupole contamination, so that stable sensitivity and mass spectra can be obtained even when samples containing many matrices are analyzed.

Operation

Smart MRM
Smart MRM makes method development quick and easy. Whether starting from scratch to optimize transitions and collision energies for new compounds, or starting from an MRM database of known target analytes to build a custom MRM method, Smart MRM takes the stress and difficulty out of method development.

Smart Database
The Shimadzu «Smart Database» is a database file for creating the method files using «Smart MRM» function. In addition to compound information and transitions, retention index can be registered in the database file. Method creation can be proceeded without calculating the retention time by analyzing the standard samples when using the Automatic Adjustment Retention Time (AART) function. In addition to MRM information, Scan and SIM ion information, mass spectra and calibration curve information from the internal standard method can also be registered in the database file. This allows users to create their own database easily.

LabSolutions Insight
LabSolutions Insight quantitative analysis support software includes functionality for enhancing the throughput of multianalyte data analysis, making it especially helpful for routine analysis.

Productivity

Active-Time Management™ That Accurately Determines Operation Time
Time Management during Instrument Startup/Shutdown

The mass spectrometer has to be operated in a vacuum condition, the startup and stopping of the system takes time depending on the condition. Determining this can be a challenge. Since the amount of time that the system takes when starting up or stopping is displayed in real time, it is easy to accurately determine when maintenance of the ion source or analysis is possible. Moreover, tasks that until now needed to be performed by the user, such as leak checks upon system startup and auto tuning, are now performed automatically.

Time Management during Injection Port Maintenance
The Easy sTop function, used to safely maintain the sample injection port without releasing the vacuum, displays the remaining time (coolingdown time) when the septum or the insert can be replaced in real time. Maintenance time can be minimized by understanding the accurate remaining time.
Furthermore, by using a ClickTek nut on the top of the sample injection port, the port can be opened or closed without tools, by simply using fingers to twist a lever. That enables faster and easier insert replacement than ever before.

Time Management for Continuous Analysis
By displaying the time required for continuous analysis in real time, the time when the current continuous analysis will finish can be accurately confirmed. This increases the instrument operating time (active time) by reducing standby time required during continuous analysis or while switching between different users. In addition, because this function makes it easier to schedule the timing for analysis preparations, such as sample preparation and pretreatment, based on the finish time of the previous analysis, it enables analytical processes to be performed more efficiently, which can help improve work-life balance.

Simple Column Replacement Using the Twin Line MS System
By connecting the outlet ends of two different columns to the MS at the same, different application data can be acquired without shutting OFF the MS vacuum.
CID gas control is a method parameter, allowing acquisition of GC-MS and GC-MS/MS data in the same batch.

Optional Units

Optional Units Enable a Variety of System Configurations
For GC-MS/MS analysis, different system configurations may be required depending on the application and sample-introduction needs. The GCMS-TQ8040 NX offers a wide variety of system configurations and sample-introduction devices to enable an expanded range of applications.

Smart EI/CI Ion Source Easily Switches Between EI and CI Methods
The Smart EI/CI ion source has been developed in order to acquire CI data without switching the ion source, and without losing the sensitivity of EI, which is most commonly used. Even when it is difficult to perform identification with the EI mode using the mass spectral library, molecular weight information can be obtained from CI data, thus helping in the estimation of unknown compounds.

DI-2010 Direct Inlet System
Direct sample injection (DI) is a method in which a sample is injected directly into the ion source without passing through the gas chromatograph (GC). This is an effective method for measuring the mass spectra of synthetic compounds, and can be used easily with a typical GC-MS configuration. By using this in combination with Smart EI/CI ion source, EI and CI mass spectra can easily be collected.

Videos

Introduction to Function with the Videos

Shimadzu’s GCMS-TQ8040 NX: Everything you always wanted to know about SmartMRM, MRM Optimization, the Smart Database Series, and more.»
1. Smart MRM

This describes Smart MRM, which allows you to use the high sensitivity of MRM analysis to analyze more than 400 components in a single run.