Shim-pack Bio Diol & IEX Columns
Описание
Shim-pack Bio Diol & IEX Columns
Solution for Analysis of Peptides, Oligonucleotides and Biopharmaceuticals
The accurate analysis of biopharmaceuticals compounds is required for developing higher quality biopharmaceuticals. Shim-pack Bio
Diol and IEX columns will improve the accuracy of the characterization of peptides, oligonucleotide and biopharmaceuticals.
Shim-pack Bio Diol : Size Exclusion Chromatography Columns
With different pore sizes, Shim-pack Bio Diol LC columns are effective for analysis of aggregates and fragments of mAb, oligonucleotides and carbohydrates.
| Shim-pack Bio Diol | Diol-60 | Diol-120 | Diol-200 | Diol-300 |
|---|---|---|---|---|
| Particle | Silica | |||
| Ligand | Dihydroxypropyl(Diol) | |||
| Particle Size | 3 μm，5 μm | 2 μm，3 μm，5 μm | ||
| Pore Size | 6 nm | 12 nm | 20 nm | 30 nm |
| pH Range | 5.0 — 7.5 | |||
| Molecular Weight Range |
below 10,000 | 1,000 — 100,000 | 5,000 — 300,000 | 20,000 — 1,000,000 |
Shim-pack Bio IEX : Ion Exchange Chromatography Columns
Shim-pack Bio IEX Columns are available in Q (quaternary ammonium) and SP (sulfopropyl) chemistries and are based on porous (Q and SP columns) and non-porous (Q-NP and SP-NP columns) hydrophilic polymers with low nonspecific adsorption. The porous particles offer excellent binding capacity with exceptionally high efficiency and the non-porous particles offer high efficiency and exceptional resolution.
Analysis of Synthesized Oligonucleotide (Single Strand DNA) using Shim-pack BIO IEX Q-NP
| Shim-pack Bio IEX | Q-NP | SP-NP | Q | SP |
|---|---|---|---|---|
| Particle | hydrophilic non-porous polymer | hydrophilic non-porous polymer | ||
| Particle Size | 3 μm，5 μm | 5 μm | ||
| Ligand | -CH2N+(CH3)3 | -(CH2)3SO3— | -CH2N+(CH3)3 | -(CH2)3SO3— |
| pH Range | 2 — 12 | |||
