CLAM-2030
Fully Automated Sample Preparation Module for LCMS™ Based on Shimadzu’s Extensive Experience with Clinical Examination Systems for Blood Coagulation Analysis
- Описание
- Video
- Applications
- Benefits
- Features
Описание
Simply Place Blood Collection Tubes in Position and the Module Automatically Performs Everything from Sample Pretreatment to LCMS Analysis
Achieves Reliable Data Acquisition
- Fully automates processes from pretreatment to LCMS analysis.
- Reduces variability in internal standard substance concentration (using vials with septa installed).
- Equipped with improved and expanded accuracy control functionality.
- Reduces operator errors and risk of infection.
Eliminates the Need to Review Settings for Routine Work
- Automates processes from searching toxicological drug libraries to generating reports.*1
- Provides the optimal analytical method.*2
Further Improves Efficiency of Research or Business Processes
- Makes it easy to create or review new pretreatment protocols.
- Samples can be added or processing interrupted in an emergency.*3
- Text files can be used to load analysis requests from an LIS or output concentration values to a specified folder.
*1 Requires the LC/MS/MS forensic toxicological database or rapid toxicology screening system Ver. 2, which are sold separately.
*2 Limited to commercial LCMS analysis kits and other methods available for supply.
*3 The number of interruptions or samples that can be added is limited by the number of pretreatment vials placed.
For Research Use Only. Not for use in diagnostic procedures.
Video
Introduction Video
Testimonial Video
Applications
The follow are examples of applications using a CLAM module.
| Target Components |
|---|
| 6-acetylmorphine, Aldosterone, Amikacin, Amiodarone, Amisulpride, Amphetamine, Androstenedion, Anhydroecgonine methyl ester, Arbekacin, Aripiprazole, |
| 8 Barbiturate drug and Bromovalerylurea, BDB, Benzoylecgonine, 39 Benzodiazepines and their metamolites, Bepridil, Buprenorphine, |
| Carbamazepine(CBZ), Carbamazepine10-11-epoxide, 2C-B, 2-Cl, CBZ-Diol, Cibenzoline, Ciprofloxacin, Clopazine, Cocaethylene, Cocaine, Codeine, Corticosterone, Cortisol, Cyclosporine, |
| Daptomycin, Dehydroaripiprazole, 11-Deoxycortisol, Desmethylclopazine, Dextromethorphan, DHEA, DHEA-S, Diazepam, Dihydrocodeine, DOACs (Apixaban, Rivaroxaban, Edoxaban, Dabigatran) |
| Ecgonine methylester, EDDP, Ethosuximide, Ethylmorphine, Everolimus, |
| Felbamate, Flecainide, |
| Gabapentin, Gentamicin, |
| Haloperidol, Hydoromorphone, Hydrocodone, 25-hydroxyvitamin D3, 25-hydroxyvitamin D2, Hygromycin C, |
| Kanamycin, Ketamine, |
| Lacosamide, Lamotrigine, Levetiracetam, Levofloxacin, Levomepromazine, Linezolid, |
| 6-MAM, MBDB, MDA, MDEA, MDMA, Melperone, Mephedrone, Metanephrin, Methadone,Methamphetamine, Methaqualone, Methcathinone, Methiopropamine, 3,4-Methylenedioxypyrovalerone, Methylphenidate, Mexiletine Morphine, m-CPP, 4-MTA, |
| Naloxone,Naltrexone, N-Desmethylolanzapine, NDMS, Neomycin B, Nimetazepam, Norbuprenorphine, Norephedrine, Norfenfluramine, Norketamine Noroxycodone, normetanephrin, Norpseudoephedrine, Norquetiapine, n-Desethylamiodarone, |
| 10-OH-CBZ, 17-OH-Progesterone, 9-OH-Risperidone, Olanzapine, Oxacarbazepine, Oxycodone, |
| Paromycin, PEMA, Perampanel, Perazine, Phencyclidine, Phenobarbital, Phenytoin, Pholcodine, Pilsicainide, Pipamperone, Pregabalin, Primidone, Progesterone, Promethazine, Propoxyphene, Pyridoxal-5′-Phoshate (P5P), |
| Quetiapine Risperidone, |
| Rapamycin (Sirolimus), Retigabine, Ritalinic acid, Rufinamide, |
| Sertindole Sulpiride, Sotalol, Stiripentol, Streptomycin, Sultiame, |
| Tacrolimus (FK 506), Teicoplanin, Teststerone, Thiamin Pyrophosphate (TPP), Thioridazine, Tiagabine, Topiramate, 12 Tri-/Tetra-cyclic antidessant, |
| Valpronic acid, Vancomycin, |
| Ziprasidone, Zonisamide, Zotepine Zuclopenthixol, (Z) -Chorprothixene |
For Research Use Only. Not for use in diagnostic procedures.
Benefits
Reduces Operator Errors and Risk of Infection During Manual Operations
Reduces Operator Errors
By simply uncapping blood collection tubes (or sample cups), placing the pretreatment vials in the system, and requesting analysis, the system performs all other process steps automatically, from pretreatment to LCMS analysis. With an LCD touch panel screen and a user interface that requires no instruction manual, the system helps ensure reliable and rapid operations with minimal operator errors due to manual operations.
（1）Carousel for samples and reagents
（2）Racks for pretreatment vials
（3）Dispensing probe for samples
（4）Dispensing probe for reagents
Reduces Infection Risk
The CLAM-2030 minimizes human contact with potentially hazardous samples through automation. Following pretreatment, solid and liquid waste are contained within the body of the CLAM-2030 and collected. Integrated sensors alert users through the software that waste levels are high and require emptying.
For Research Use Only. Not for use in diagnostic procedures.
Features
Automates All Process Steps, from Pretreating to Measuring Blood, Urine, Serum and Plasma Samples
- Enables seamless analysis and management of samples throughout the entire process from pretreatment to LC/MS/MS measurement.
- Automation means samples can be analyzed automatically at nights or on days off.
Supports Measuring a Wide Range of Compounds
- Flexible HPLC and MS configuration to meet application need.
- Measure hundreds of compounds in a single analysis.
- Easily change between different methods.
Checking Various Measurement Results Is Easy
- Facilitates data review and flags inconsistent data and instrument conditions.
For Research Use Only. Not for use in diagnostic procedures.
